Solana® GBS Assay
Solana® Molecular Testing Platform
Solana® GBS Assay

The Solana GBS assay is an in vitro diagnostic test for the direct, qualitative detection of group B Streptococcus from vaginal/rectal swabs following 18 to 24 hours incubation in LIM or Carrot broth cultures.

The assay utilizes helicase-dependent amplification (HDA) for the amplification of a highly conserved fragment of the Thiolase (atoB) gene sequence and is intended for use only with the Solana instrument.

An overnight LIM or Carrot broth culture enriched from a swab is lysed by simple heat treatment, aliquoted and added to a Reaction Tube containing lyophilized mix of HDA reagents including primers specific for the amplification of a fragment from the conserved region of the Thiolase (atoB) DNA.

The target sequence is amplified inside Solana by specific primers and detected by a specific fluorescence probe included in the Reaction Tube. A competitive process control (PRC) is included in the Lysis Tube to monitor sample processing, inhibitory substances in clinical samples, reagent failure or device failure. The PRC is amplified by the target-specific primers and detected by a PRC specific fluorescence probe.

Results are displayed on the touchscreen, can be saved to the instrument, printed, and are capable of being sent to the LIS and exported through one of Solana’s four USB ports. Solana GBS is supported by the power of the Virena® System

Solana GBS assay 
Catalog number: M311 
Kit size/Case size: 48 tests

Quidel Molecular GBS Control Set 
Catalog number: M116 
Kit size/Case size: 20 reactions

Contact us

Solana® Molecular Testing Platform
Solana® GBS Assay
Solana® GBS Assay

The Solana GBS assay is an in vitro diagnostic test for the direct, qualitative detection of group B Streptococcus from vaginal/rectal swabs following 18 to 24 hours incubation in LIM or Carrot broth cultures.

The assay utilizes helicase-dependent amplification (HDA) for the amplification of a highly conserved fragment of the Thiolase (atoB) gene sequence and is intended for use only with the Solana instrument.

An overnight LIM or Carrot broth culture enriched from a swab is lysed by simple heat treatment, aliquoted and added to a Reaction Tube containing lyophilized mix of HDA reagents including primers specific for the amplification of a fragment from the conserved region of the Thiolase (atoB) DNA.

The target sequence is amplified inside Solana by specific primers and detected by a specific fluorescence probe included in the Reaction Tube. A competitive process control (PRC) is included in the Lysis Tube to monitor sample processing, inhibitory substances in clinical samples, reagent failure or device failure. The PRC is amplified by the target-specific primers and detected by a PRC specific fluorescence probe.

Results are displayed on the touchscreen, can be saved to the instrument, printed, and are capable of being sent to the LIS and exported through one of Solana’s four USB ports. Solana GBS is supported by the power of the Virena® System

Solana GBS assay 
Catalog number: M311 
Kit size/Case size: 48 tests

Quidel Molecular GBS Control Set 
Catalog number: M116 
Kit size/Case size: 20 reactions

Contact us

Features & benefits

Rapid method of isothermal nucleic acid amplification that does not require thermocycling with RT-HDA technology.

Easy-to-use format, just add processed sample to rehydrate using Lyophilized Master Mix reagent.

Small, easy-to-use instrument eliminates the need for dedicated molecular space and costly capital equipment, allowing for testing in smaller labs.

Find what you need

To access safety data sheets, package inserts, quick reference guides and all other technical and promotional materials, visit our technical documents library.

 

Technical documentation

Product specifications
Sample type Vaginal/rectal swab specimens cultured for 18 to 24 hours in either LIM or Carrot broth
Time to results 30 minutes 
Reagent storage conditions Lysis, Dilution and Reaction Tubes; 2˚C to 8˚C
Controls storage conditions 2˚C to 8˚C
Clinical Sensitivity (LIM broth) 100%
Clinical Specifity (LIM broth) 95.9% 
Clinical Sensitivity (Carrot broth) 100%
Clinical Specifity (Carrot broth) 96%
LOD 2.6 x 105 CFU/mL

Solana in action

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