Factor Ba Protein
Purified human Factor Ba protein
Product Specifications
| Citations | 0 |
|---|---|
| Description |
Purified human Factor Ba protein |
| Storage | Store at -70°C or below. Avoid freeze/thaw. |
| Form |
Frozen liquid. Phosphate-buffered saline, pH 7.3. No preservative, 0.22 µm filtered. |
| Concentration | 1.0 mg/mL (refer to CoA for lot specific concentration) |
| Applications |
See citations and technical data sheet for application info. |
Ordering Information
| Catalog Number | A422 |
|---|---|
| Catalog Number (CE) | N/A |
| Size | 100 µL |
| Price (USD) | $290.00 |
| Price (EURO) | 260,00 € |
Contact us
| US Phone | +1 (858) 552 1100 |
|---|---|
| EU Phone | +353 (91) 412 474 |
| US Email | contact-us@quidelortho.com |
| EU Email | contact-emea@quidelortho.com |
- Specifications
- Citations
- Certificate of Analysis
Specifications
| Description |
Purified human Factor Ba protein |
|---|---|
| Size | 100 µL |
| Storage |
Store at -70°C or below. Avoid freeze/thaw. |
| Form | Frozen liquid. Phosphate-buffered saline, pH 7.3. No preservative, 0.22 µm filtered. |
| Concentration | 1.0 mg/mL (refer to CoA for lot specific concentration) |
| Applications | See citations and technical data sheet for application info. |
| Purity | >95% by SDS-PAGE |
| Source |
Normal human serum |
| Activity | No activity |
| Molecular Weight | 33,000 Da (single chain) |
| Background |
Factor Ba is the fragment of complement factor B that results from activation of the alternative pathway. The factor Ba fragment from factor B which was purified from normal human serum. Complement factor B is a glycosylated protein composed of a single 93,000 Da polypeptide chain. Factor B is an essential component of the alternative pathway of complement activation and is found in plasma at approximately 200 µg/mL. In the presence of Mg++ factor B binds to C3b and the C3bB complex can be activated by factor D, a serine protease that circulates as an active trypsin-like serine protease. Cleavage of factor B by factor D causes the release of the Ba fragment (33,000 Da) and leaves the 60,000 Da Bb fragment bound to C3b. |
Citations
| Title | Year | Applications | Sample Species | Sample | Sample Details |
|---|
Certificate of Analysis
