C1q Depleted Sera

Normal human serum depleted of complement C1q protein.

Product Specifications

Citations	18
Description	Normal human serum depleted of complement C1q protein.
Storage	Store at -70°C or below. Minimize freeze/thaw cycles.
Form	Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.
Concentration	>50 mg protein/mL (refer to CoA for lot specific concentration).
Applications	See citations and technical data sheet for application info.

Technical Documents

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.

Catalog Number	A509
Catalog Number (CE)	N/A
Size	1.0 mL
Price (USD)	$225.00
Price (EURO)	175,00 €

Contact us

US Phone	+1 (858) 552 1100
EU Phone	+353 (91) 412 474
US Email	customerservice@quidelortho.com
EU Email	EMEACustomerService@quidelortho.com

Specifications
Citations
Certificate of Analysis

Specifications

Description	Normal human serum depleted of complement C1q protein.
Size	1.0 mL
Storage	Store at -70°C or below. Minimize freeze/thaw cycles.
Form	Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.
Concentration	>50 mg protein/mL (refer to CoA for lot specific concentration).
Applications	See citations and technical data sheet for application info.
Purity	No C1q detectable by immunodiffusion.
Source	Normal human serum
Activity	>80% versus normal human serum standard.
Molecular Weight	N/A
Background	Normal human serum depleted of complement C1q protein by immunoaffinity chromatography. The product is tested for the absence of C1q by functional assays for classical pathway activity and for C1q protein by double immunodiffusion.

Citations

Title	Year	Applications	Sample Species	Sample	Sample Details
Vaccinia virus extracellular enveloped virion neutralization in vitro and protection in vivo depend on complement	2009	Complement Activation Assay	Cell Culture	Vero E6 cells
Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation	2009	ELISA	N/A	Purified protein	SLRP
Complement activation by bisretinoid constituents of RPE lipofuscin	2009	ELISA	Human	Serum
Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells	2009	WB	Cell Culture	DU-145 Cells
The C-type lectin of the aggrecan G3 domain activates complement	2013	ELISA	Human	Serum	C1q Depleted
Complement c5a generation by staphylococcal biofilms	2013	FC	Human	Serum	Staphylococcus epidermidis incubated
Bioactive lysophospholipids generated by hepatic lipase degradation of lipoproteins lead to complement activation via the classical pathway	2014	ELISA	Human	Serum
Exploitation of the complement system by oncogenic Kaposi's sarcoma-associated herpesvirus for cell survival and persistent infection	2014	IF	Cell Culture	TIME-KSHV cells
Characterization of BCAM0224, a multifunctional trimeric autotransporter from the human pathogen Burkholderia cenocepacia	2014	Serum Bactericidal Assay	Human	Serum	Burkholderia cenocepacia incubated
Human IgG is produced in a pro-form that requires clipping of C-terminal lysines for maximal complement activation	2015	CDC Assay	Human	Daudi Cells
Rapid and efficient purification of ficolin-2 using a disposable CELLine bioreactor	2015	FC	Human	Serum	Streptococcus pneumoniae
The relevance of coagulation factor X protection of adenoviruses in human sera	2016	ELISA	Human	Serum	Adenovirus incubated
Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells	2017	WB	Cell Culture	RPE Cells
rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs	2018	ELISA	Human	Serum	Fc activation
The Surface-Exposed Protein SntA Contributes to Complement Evasion in Zoonotic Streptococcus suis	2018	ELISA	N/A	C1q Depleted Sera
EGFR modulates complement activation in head and neck squamous cell carcinoma	2020	IF	Cell Culture	HNSCC Cells
Inflammasome-Dependent Peroxiredoxin 2 Secretion Induces the Classical Complement Pathway Activation	2021	Complement Activation Assay	Human	Serum
Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking	2021	ELISA	Human	Plasma

Certificate of Analysis

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