sC5b-9 Antibody (Polyclonal - neoantigen)

A rabbit antiserum raised against human complement SC5b-9 protein.


Product Specifications

Citations 0
Clonality

Polyclonal

Immunogen Highly purified human SC5b-9
Applications See citations and technical data sheet for application info.
Concentration 5 mg/mL
Conjugate Unconjugated
Cross Reactivity

Human

Ordering Information

For Research Use Only in the United States. Not for use in diagnostic procedures.
Catalog Number A317
Catalog Number (CE) N/A
Size 250 µL
Price (USD) $260.00
Price (EURO) 210,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

A rabbit antiserum raised against human complement SC5b-9 protein.

Size 250 µL
Concentration

5 mg/mL

Applications See citations and technical data sheet for application info.
Form Liquid. Phosphate-buffered saline, pH 7.2. ≤ 0.1% Sodium Azide
Clonality Polyclonal
Immunogen Highly purified human SC5b-9
Conjugate Unconjugated
Cross Reactivity Human
Isotype Rabbit IgG
Purity IgG Purified
Source

Rabbit

Specificity The Anti-Human SC5b-9 Neoantigen IgG fraction is stringently absorbed with normal complement proteins to be monospecific for the SC5b-9 neoantigen. The purified IgG Fraction was tested by immunodiffusion and determined to be monospecific for the SC5b-9 neoantigen.
Storage

Short term (30 days) 4˚C. Long term at or below –20˚C.

Background

Activation of the terminal complement pathway is the result of activation of any of the three pathways in the complement system: the classical, alternative and lectin pathways. In this process, complement protein C5 is cleaved to C5b and may then interact sequentially with complement proteins C6, C7, C8 and C9 forming the terminal complement complex (TCC). In the presence of a membrane, these complexes can form transmembrane pores causing complement mediated cytolysis. In the absence of a target membrane, the TCC binds to naturally occurring regulatory serum proteins and the resulting products are commonly called SC5b-9.

Citations

Title Year Applications Sample Species Sample Sample Details