Rabbit YKL-40 antibody

A rabbit polyclonal antibody specific to human YKL-40.


Product Specifications

Citations0
Clonality

Polyclonal

Immnogen

Recombinant human YKL-40

Applications

See citations and technical data sheet for application info.

Concentration≥1 mg/mL
ConjugateUnconjugated
Cross Reactivity

Cynomolgus monkey and rhesus macaque

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog Number4815
Catalog Number (CE)N/A
Size100 µl
Price (USD)$375.00
Price (EURO)330,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

A rabbit polyclonal antibody specific to human YKL-40.

Size

100 µl

Concentration≥1 mg/mL
ApplicationsSee citations and technical data sheet for application info.
FormLiquid. 50 mM Phosphate Buffered Saline
ClonalityPolyclonal
Immunogen

Recombinant human YKL-40

ConjugateUnconjugated
Cross ReactivityCynomolgus monkey and rhesus macaque
Isotype

Rabbit IgG

Purity

>85% by SDS PAGE

SourceRabbit
Specificity

This antibody was tested by various immunoassays to be specific to human YKL-40.

Storage

Short term (30 days) 4°C. Long term at –70°C.

Background

YKL-40, a member of the mammalian chitinase like protein class, is a 40 kD heparin binding glycoprotein. It shares amino acid sequence homology to non-mammalian chitinases but demonstrates no chitinase activity. The name YKL-40 is derived from the protein’s molecular weight and three N-terminus amino acids (tyrosine, lysine and leucine). The biological function of YKL-40 remains largely unknown and is a field of extensive scientific debate. YKL-40 has been shown to be a potent growth factor for connective tissue cells and a potent migration factor for endothelial cells. Several research studies have demonstrated substantial levels of YKL-40 in environments with inflammation or where substantial remodeling of the extracellular matrix (ECM) occurs, including various cancers, active rheumatoid arthritis, inflammatory bowel diseases, severe bacterial infections, and liver fibrosis.

Citations

TitleYearApplicationsSample SpeciesSampleSample Details