MICROVUE Mouse/Rat FGF-23 ELISA (Intact)

The MICROVUE Mouse FGF-23 (Intact) ELISA Kit is for the measurement of intact FGF-23 in plasma, serum, or cell culture media.


Product Specifications

Citations 9
Specimen

Plasma, Serum, or Cell Culture Supernatent 40 µL

LLOQ 0.006 ng/mL
ULOQ N/A
Assay Time 3.5 hours
Cross Reactivity

None

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog Number 60-6800
Catalog Number (CE)  
Size 96 wells/test
Price (USD) $935.00
Price (EURO) 835,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcustomerservice@quidelortho.com
EU EmailEMEACustomerService@quidelortho.com

Specifications

Description

The MICROVUE Mouse FGF-23 (Intact) ELISA Kit is for the measurement of intact FGF-23 in plasma, serum, or cell culture media.

Size 96 wells/test
Form

96 well plate with 12 eight-well strips in a resealable foil pouch

Specimen Plasma, Serum, or Cell Culture Supernatent 40 µL
Limit of Detection (LOD) 0.006 ng/mL
Lower Limit of Quantitation (LLOQ) 0.006 ng/mL
Upper Limit of Quantitation (ULOQ) N/A
Intra Assay 2.3 - 4.4%
Inter Assay 4.0%
Standards 6
Controls 2
Sample Values

N/A

Assay Time 3.5 hours
Cross Reactivity

None

Storage

Store unopened kit between 2°C to 8°C. Refer to manual for storing individual components

Background

Fibroblast growth factor 23 (FGF-23), which is produced by bone cells, is a novel member of a large family of related proteins. Its gene encodes a 251 amino acid protein. The amino-terminal portion of FGF-23 (aa 1-24) is hydrophobic and is likely to serve as a signal peptide allowing its secretion into the blood circulation. Its carboxyl-terminal portion (aa 180-251) shares only limited amino acid homology with other members of the FGF family of proteins.

Citations

Title Year Applications Sample Species Sample Sample Details

The intestinal phosphate transporter NaPi-IIb (Slc34a2) is required to protect bone during dietary phosphate restriction

2017

ELISA

Mouse

Plasma

1,25-Dihydroxyvitamin D Maintains Brush Border Membrane NaPi2a and Attenuates Phosphaturia in Hyp Mice

2019

ELISA

Mouse

Serum

1,25-Dihydroxyvitamin D Maintains Brush Border Membrane NaPi2a and Attenuates Phosphaturia in Hyp Mice

2019

ELISA

Mouse

Urine

A G protein-coupled, IP3/protein kinase C pathway controlling the synthesis of phosphaturic hormone FGF23

2019

ELISA

Mouse

Serum

Elevated FGF23 and disordered renal mineral handling with reduced bone mineralization in chronically erythropoietin over-expressing transgenic mice

2019

ELISA

Mouse

Plasma

Human Heterozygous ENPP1 Deficiency Is Associated With Early Onset Osteoporosis, a Phenotype Recapitulated in a Mouse Model of Enpp1 Deficiency

2019

ELISA

Mouse

Plasma

Selective pharmacological inhibition of the sodium-dependent phosphate cotransporter NPT2a promotes phosphate excretion

2020

ELISA

Rat

Plasma

Comprehensive Expression Analysis of Cardiac Fibroblast Growth Factor 23 in Health and Pressure-induced Cardiac Hypertrophy

2024

ELISA

Mouse

Plasma

Pressure-induced Cardiac Hypertrophy

Phosphate Restriction Prevents Metabolic Acidosis and Curbs Rise in FGF23 and Mortality in Murine Folic Acid-Induced AKI

2024

ELISA

Mouse

Plasma

Murine-Folic Acid-Induced Acute Kidney Injury

Organic phosphate but not inorganic phosphate regulates Fgf23 expression through MAPK and TGF-ꞵ signaling

2024

ELISA

Cell Culture

MC3T3-E1 Cells

Targeted Deletion of Fibroblast Growth Factor 23 Rescues Metabolic Dysregulation of Diet-induced Obesity in Female Mice

2024

ELISA

Mouse

Serum

Obesity

Targeted Deletion of Fibroblast Growth Factor 23 Rescues Metabolic Dysregulation of Diet-induced Obesity in Female Mice

2024

ELISA

Mouse

Serum

Obesity

Phosphorus-independent role of FGF23 in erythropoiesis and iron homeostasis

2024

ELISA

Mouse

Serum

Fibroblast growth factor 23 and fibroblast growth factor receptor 4 promote cardiac metabolic remodeling in chronic kidney disease

2025

ELISA

Mouse

Plasma

Chronic Kidney Disease

The Roxadustat (FG-4592) ameliorates tubulointerstitial fibrosis by promoting intact FGF23 cleavage

2025

ELISA

Rat

Plasma

Thromboxane A2 or Activated Platelets Slightly Lower Fgf23 Expression in vitro

2025

ELISA

Cell Culture

UMR-106 Cells

The AMPK/ULK1/autophagy pathway: FGF23's weapon against GSDME-mediated pyroptosis in folic acid-induced acute kidney injury

2025

ELISA

Mouse

Serum

Acute kidney injury

Disruption of the FGFR1-FGF23-Phosphate Axis and Targeted Therapy in a Murine Model of Osteoglophonic Dysplasia

2025

ELISA

Mouse

Plasma

Osteoglophonic dysplasia

Lysophosphatidic Acid Synergizes With 1,25-Dihydroxyvitamin D to Promote Fibroblast Growth Factor-23 Synthesis via MAPK Signaling and Induction of the IL12A Gene

2026

ELISA

Mouse

Serum

The renal response to FGF23 shifts from phosphaturia toward inflammation in kidney disease

2026

ELISA

Mouse

Serum