C1q Depleted Sera

Normal human serum depleted of complement C1q protein.

Product Specifications

Citations18
Description

Normal human serum depleted of complement C1q protein.

Storage

Store at -70°C or below. Minimize freeze/thaw cycles.

Form

Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.

Concentration

>50 mg protein/mL (refer to CoA for lot specific concentration).

Applications

See citations and technical data sheet for application info.

Technical Documents

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog NumberA509
Catalog Number (CE)N/A
Size1.0 mL
Price (USD)$195.00
Price (EURO)150,00 €
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US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

Normal human serum depleted of complement C1q protein.

Size1.0 mL
Storage

Store at -70°C or below. Minimize freeze/thaw cycles.

Form

Frozen liquid. 10 mM sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered.

Concentration>50 mg protein/mL (refer to CoA for lot specific concentration).
ApplicationsSee citations and technical data sheet for application info.
PurityNo C1q detectable by immunodiffusion.
SourceNormal human serum
Activity>80% versus normal human serum standard.
Molecular WeightN/A
Background

Normal human serum depleted of complement C1q protein by immunoaffinity chromatography. The product is tested for the absence of C1q by functional assays for classical pathway activity and for C1q protein by double immunodiffusion.

Citations

TitleYearApplicationsSample SpeciesSampleSample Details

Inflammasome-Dependent Peroxiredoxin 2 Secretion Induces the Classical Complement Pathway Activation.

2021Complement Activation AssayHuman

Serum

N/A

Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking.

2021ELISAHuman

Plasma

N/A

EGFR modulates complement activation in head and neck squamous cell carcinoma.

2020IFCell Culture

HNSCC Cells

N/A

rIgG1 Fc Hexamer Inhibits Antibody-Mediated Autoimmune Disease via Effects on Complement and FcγRs

2018ELISAHuman

Serum

Fc activation

The Surface-Exposed Protein SntA Contributes to Complement Evasion in Zoonotic Streptococcus suis

2018ELISAN/A

C1q Depleted Sera

N/A

Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells

2017WBCell Culture

RPE Cells

N/A

The relevance of coagulation factor X protection of adenoviruses in human sera

2016ELISAHuman

Serum

Adenovirus incubated

Human IgG is produced in a pro-form that requires clipping of C-terminal lysines for maximal complement activation

2015CDC AssayHuman

Daudi Cells

N/A

Rapid and efficient purification of ficolin-2 using a disposable CELLine bioreactor

2015FCHuman

Serum

Streptococcus pneumoniae

Bioactive lysophospholipids generated by hepatic lipase degradation of lipoproteins lead to complement activation via the classical pathway

2014ELISAHuman

Serum

N/A

Exploitation of the complement system by oncogenic Kaposi's sarcoma-associated herpesvirus for cell survival and persistent infection

2014IFCell Culture

TIME-KSHV cells

N/A

Characterization of BCAM0224, a multifunctional trimeric autotransporter from the human pathogen Burkholderia cenocepacia

2014Serum Bactericidal AssayHuman

Serum

Burkholderia cenocepacia incubated

The C-type lectin of the aggrecan G3 domain activates complement

2013ELISAHuman

Serum

C1q Depleted

Complement c5a generation by staphylococcal biofilms

2013FCHuman

Serum

Staphylococcus epidermidis incubated

Vaccinia virus extracellular enveloped virion neutralization in vitro and protection in vivo depend on complement

2009Complement Activation AssayCell Culture

Vero E6 cells

N/A

Complement activation by bisretinoid constituents of RPE lipofuscin.

2009ELISAHuman

Serum

N/A

Short leucine-rich glycoproteins of the extracellular matrix display diverse patterns of complement interaction and activation

2009ELISAN/A

Purified protein

SLRP

Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cells

2009WBCell Culture

DU-145 Cells

N/A

Certificate of Analysis

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