MICROVUE™ Factor I EIA
The MICROVUE Factor I EIA is an enzyme immunoassay for the quantitative measurement of complment Factor I.
Product Specifications
| Citations | 0 |
|---|---|
| Specimen |
Serum/EDTA Plasma 10 μL |
| LLOQ | 1.6 ng/mL |
| ULOQ | 82.1 ng/mL |
| Assay Time | 2.5 hours |
| Cross Reactivity |
None |
Ordering Information
| Catalog Number | A041 |
|---|---|
| Catalog Number (CE) | |
| Size | 96 wells/test |
| Price (USD) | $745.00 |
| Price (EURO) | 670,00 € |
Contact us
| US Phone | +1 (858) 552 1100 |
|---|---|
| EU Phone | +353 (91) 412 474 |
| US Email | contact-us@quidelortho.com |
| EU Email | contact-emea@quidelortho.com |
- Specifications
- Citations
- Certificate of Analysis
Specifications
| Description |
The MICROVUE Factor I EIA is an enzyme immunoassay for the quantitative measurement of complment Factor I. |
|---|---|
| Size | 96 wells/test |
| Form |
96 well plate with 12 eight-well strips in a resealable foil pouch |
| Specimen | Serum/EDTA Plasma 10 μL |
| Limit of Detection (LOD) | 0.5 ng/mL |
| Lower Limit of Quantitation (LLOQ) | 1.6 ng/mL |
| Upper Limit of Quantitation (ULOQ) | 82.1 ng/mL |
| Intra Assay | 3% |
| Inter Assay | 5% |
| Standards | 5 |
| Controls | 2 |
| Sample Values |
None |
| Assay Time | 2.5 hours |
| Cross Reactivity |
None |
| Storage |
Store the unopened kit at 2°C to 8°C. Refer to Product Insert for additional storage details. |
| Background |
Factor I (FI) is a negative regulatory protein of the complement system, and inhibits all pathways by cleaving activation components C4b and C3b. FI is a soluble protein, and circulates freely in the blood, though in an inactive state. Once FI is in the presence of a variety of co-factors it activates and inhibits complement activation. These co-factors include Factor H (only for C3b cleavage), MCP (CD46), CD35, and C4BP. The MICROVUE Factor I EIA measures the concentration of Factor I in serum or plasma. It uses a monoclonal antibody to Factor I, which is subsequently detected with an HRP-conjugated antibody that bind to another epitope of Factor I. This test, which provides a rapid, highly specific and quantitative procedure for measuring Factor I levels, is designed for investigations studying the role or status of complement pathway regulation in numerous research settings. |
Citations
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