C9 Antibody (Monoclonal), Biotinylated

A biotin conjugated murine monoclonal antibody to an epitope on C9.


Product Specifications

Citations0
Clonality

Monoclonal

Immnogen

Purified human protein.

Applications

See citations and technical data sheet for application info.

Concentration0.2 mg/mL
ConjugateBiotin
Cross Reactivity

Human, Baboon, Bovine, Chicken, Guinea pig, Hamster, Horse

Ordering Information

For Research Use Only in the United States. Not for use in diagnostic procedures.
Catalog NumberA709
Catalog Number (CE)N/A
Size250 µL
Price (USD)$365.00
Price (EURO)330,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

A biotin conjugated murine monoclonal antibody to an epitope on C9.

Size

250 µL

Concentration0.2 mg/mL
ApplicationsSee citations and technical data sheet for application info.
FormLiquid. Phosphate Buffered Saline (pH 7.0 ± 0.2), 1% Bovine Serum Albumin, with ≤ 0.1% Sodium Azide.
ClonalityMonoclonal
Immunogen

Purified human protein.

ConjugateBiotin
Cross ReactivityHuman, Baboon, Bovine, Chicken, Guinea pig, Hamster, Horse
Isotype

IgG2bk

Purity

≥ 95% by SDS PAGE

SourceMouse
Specificity

This monoclonal antibody was raised against purified human C9. It is specific for an antigen expressed on the C9 but not expressed in MAC. It will inhibit the lysis of EA and will not bind to membrane associated MAC.

Storage

Short term (30 days) 4˚C. Long term at or below –20˚C.

Background

Complement protein, C9 is a single-chain glycoprotein with a molecular weight of 71 kD. The C9 protein is present in serum at a concentration of approximately 55 μg/ml. Upon activation of the Classical, Lectin or Alternative Complement Pathways, C9 becomes integrated into the Terminal Complement Complex (TCC). The Terminal Complement Complex (TCC) is the general term for both membrane bound C5b-9 (or Membrane Attack Complex; MAC) and fluid phase SC5b-9. Assessment of the TCC is an excellent marker for qualifying the extent of Terminal Pathway activation in vivo or in vitro. TCC can be deposited on the surface of transformed cells, biomaterials, and a variety of other surfaces.

Citations

TitleYearApplicationsSample SpeciesSampleSample Details