Case Studies

COVID-19 Antibody Scientific Review Series

Jun 11, 2020

Welcome to Ortho’s COVID-19 Antibody Scientific Series, where Science and Medical experts from Ortho Clinical Diagnostics will review currently available information and share perspectives on critical topics related to antibody testing for COVID-19.

Antibody Tests and the COVID-19 Pandemic: What do they really mean as the world yearns for a return to normal life?

Dr. Fernando Chaves, Global Head, Medical and Scientific Affairs

In the first of Ortho’s COVID-19 Antibody Scientific Series, Dr. Fernando Chaves explores answers to the critical question:  Do antibodies really provide immunity against COVID-19? Read More

CDC Interim Guidelines for COVID-19 Antibody Testing: What are the implications?

Dr Lily Li, Director Medical & Scientific Affairs
Dipali Desai, Sr. Global Product Manager Infectious Disease Assays

Our second perspective in this series, Dr. Li and Ms. Desai discuss the CDC guidelines and the importance of accurate serologic methods for public health and clinical uses to monitor and respond to the COVID-19 pandemic. Read More

Neutralizing Antibodies to SARS-CoV-2: An Important Mechanism of Immunity

Dr. Lily Li, Director Medical & Scientific Affairs

Dr. Lily Li reviews the role of neutralizing antibodies in preventing viral infections and what we know about neutralizing antibodies to SARS-Cov-2. She addresses the current challenges of measuring neutralizing antibodies with neutralization assays and reviews anrecent study evaluating serological tests for their correlation with neutralization assays. See how this brings us one step closer to understanding COVID-19 immunity. Read More

Serological Testing as Aid in Diagnosis and Management of Symptomatic and Asymptomatic COVID-19 Patients

Dr. Maria-Magdalena Patru, Director, Medical and Scientific Affairs

In this article we discuss how antibody detection could contribute significantly to increasing diagnosis accuracy of recent or prior COVID-19 infections in both symptomatic and asymptomatic patients, in addition to antigen (virus or specific viral proteins) detection.  Read More

Convalescent Plasma: What the Data Shows for this Promising Potential COVID-19 Treatment

Carolina Triplett Global Product Manager, Transfusion Medicine
Dr Lily Li, Director Medical & Scientific Affairs

Dr. Li and Ms. Triplett discuss the role convalescent plasma may play in ending the pandemic including explaining the mechanism of action, pros and cons of treatment and potential applications for COVID-19 patients.  Dr. Li reviews the clinical publications including the data from the Expanded Access Program led by the Mayo Clinic.  

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