Factor D Protein
Purified human Factor D protein
Product Specifications
| Citations | 2 |
|---|---|
| Description |
Purified human Factor D protein |
| Storage | Store at -70°C or below. Avoid freeze/thaw. |
| Form |
Frozen liquid. 10 mM Sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered. |
| Concentration | 0.1 mg/mL (refer to CoA for lot specific concentration) |
| Applications |
See citations and technical data sheet for application info. |
Ordering Information
| Catalog Number | A409 |
|---|---|
| Catalog Number (CE) | N/A |
| Size | 250 µL |
| Price (USD) | $300.00 |
| Price (EURO) | 265,00 € |
Contact us
| US Phone | +1 (858) 552 1100 |
|---|---|
| EU Phone | +353 (91) 412 474 |
| US Email | contact-us@quidelortho.com |
| EU Email | contact-emea@quidelortho.com |
- Specifications
- Citations
- Certificate of Analysis
Specifications
| Description |
Purified human Factor D protein |
|---|---|
| Size | 250 µL |
| Storage |
Store at -70°C or below. Avoid freeze/thaw. |
| Form | Frozen liquid. 10 mM Sodium phosphate, 145 mM NaCl, pH 7.3. No preservative, 0.22 µm filtered. |
| Concentration | 0.1 mg/mL (refer to CoA for lot specific concentration) |
| Applications | See citations and technical data sheet for application info. |
| Purity | >95% by SDS-PAGE |
| Source |
Normal human serum |
| Activity | >95% versus normal human serum standard |
| Molecular Weight | 24,000 Da (single chain) |
| Background |
Purified human complement Factor D. Factor D is unique to the Alternative Complement Pathway. It consists of a single peptide chain with a molecular weight of 24 kD. Factor D is a specific serine protease which cleaves Factor B complexed with C3b (or hydrolyzed C3) in a single position to yield Bb and Ba. |
Citations
| Title | Year | Applications | Sample Species | Sample | Sample Details |
|---|---|---|---|---|---|
|
Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo. |
2017 | Dot Blot |
Human |
Serum |
SPIO nanoworms |
|
Inhibition of aberrant complement activation by a dimer of acetylsalicylic acid. |
2015 | ELISA, WB |
Human |
Serum |
Acetyl salicylic acid dimer 5,5'-methylenebis(2-acetoxybenzoic acid) (DAS) |