C3a Antibody (Monoclonal)

A murine monoclonal antibody to the human C3a domain of C3.

1.0-1.2 mg/mL

Mouse

Short term (30 days) 4˚C. Long term at or below –20˚C.

The human complement component, C3, consists of two disulfide-bonded subunits (Alpha – 115,000 kD and Beta – 75,000 kD). The concentration of C3 in serum is approximately 1.25 + 0.52 mg/ml. Under normal conditions, activation of either the Classical, Lectin or Alternative Complement Pathways produces C3 convertase which cleaves C3 into two fragments – C3a, an anaphylatoxin, and C3b. Quidel’s monoclonal antibodies to complement antigens were prepared using standard techniques. They are purified from mouse ascites fluid via Protein A affinity chromatography. Quidel’s Anti-Human C3a monoclonal antibody was raised against highly pure human C3 protein.