MicroVue™ Serum PYD

The MicroVue Serum PYD provides a quantitative measure of the excretion of pyridinoline cross-link (Pyd) in serum.


Product Specifications

Citations 9
Specimen

Serum 25 μL

LLOQ N/A
ULOQ N/A
Assay Time 20-26 hours
Cross Reactivity

Baboon, Cat, Cow, Dog, Guinea Pig, Horse, Mouse, Pig, Rat, Rhesus monkey

Ordering Information

For Research Use Only. Not for use in diagnostic procedures.
Catalog Number 8019
Catalog Number (CE)  
Size 96 wells/test
Price (USD) $970.00
Price (EURO) 865,00 €

Contact us

US Phone+1 (858) 552 1100
EU Phone+353 (91) 412 474
US Emailcontact-us@quidelortho.com
EU Emailcontact-emea@quidelortho.com

Specifications

Description

The MicroVue Serum PYD provides a quantitative measure of the excretion of pyridinoline cross-link (Pyd) in serum.

Size 96 wells/test
Form

96 well plate with 12 eight-well strips in a resealable foil pouch

Specimen Serum 25 μL
Limit of Detection (LOD) 0.4 nmol/L
Lower Limit of Quantitation (LLOQ) N/A
Upper Limit of Quantitation (ULOQ) N/A
Intra Assay 4.8–10.0%
Inter Assay 4.8–9.8%
Standards 1
Controls 2
Sample Values

Adult (25–55) 1.09–2.79 nmol/L

Assay Time 20-26 hours
Cross Reactivity

Baboon, Cat, Cow, Dog, Guinea Pig, Horse, Mouse, Pig, Rat, Rhesus monkey

Storage

Store unopened kit between 2°C to 8°C. Refer to manual for storing individual components

Background

Pyridinoline cross-links are an indicator of type I collagen resorption, especially bone collagen. In humans, the total pool of urinary Pyd is approximately 45% free while the remaining fraction is bound to oligopeptides ranging from small linear peptides to very large cross-linked structures in excess of 10,000 Da. The proportion of free to total cross-links appears to be constant in healthy individuals and those with metabolic bone diseases or arthritis conditions, thus providing the rationale for measuring free Pyd.